Withaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3

Fulminant hepatitis (FH) is an incurable clinical syndrome where novel therapeutics are warranted. Withaferin A (WA), isolated from herb Withania Somnifera, is a hepatoprotective agent. Whether and how WA improves D-galactosamine (GalN)/lipopolysaccharide (LPS)-induced FH is unknown. This study was...

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Detalles Bibliográficos
Autores principales: Xia, Yangliu, Wang, Ping, Yan, Nana, Gonzalez, Frank J., Yan, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878893/
https://www.ncbi.nlm.nih.gov/pubmed/33574236
http://dx.doi.org/10.1038/s41419-020-03243-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878893/
https://www.ncbi.nlm.nih.gov/pubmed/33574236
http://dx.doi.org/10.1038/s41419-020-03243-w

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