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Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 35

Oncolytic adenoviruses (OAds) are among the most promising oncolytic viruses. Almost all oncolytic adenoviruses are composed of human adenovirus serotype 5 (Ad5) (OAd5). However, expression of the primary infection receptor for Ad5, coxsackievirus-adenovirus receptor (CAR), often declines on maligna...

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Detalles Bibliográficos
Autores principales: Ono, Ryosuke, Takayama, Kosuke, Sakurai, Fuminori, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878985/
https://www.ncbi.nlm.nih.gov/pubmed/33614920
http://dx.doi.org/10.1016/j.omto.2021.01.015