Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment

The potency of cancer vaccines is often compromised by a variety of immunoinhibitory mechanisms, including stimulation of the programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) immune checkpoint pathway. Here, to overcome inhibition, we determined the potential of recombinant a...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Zhiwu, Chiu, Mei Sum, Yan, Chi Wing, Man, Kwan, Chen, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878991/
https://www.ncbi.nlm.nih.gov/pubmed/33614918
http://dx.doi.org/10.1016/j.omto.2021.01.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878991/
https://www.ncbi.nlm.nih.gov/pubmed/33614918
http://dx.doi.org/10.1016/j.omto.2021.01.010

Ejemplares similares