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Efficacy of dual carbapenem treatment in a murine sepsis model of infection due to carbapenemase-producing Acinetobacter baumannii

OBJECTIVES: To evaluate the in vivo efficacy of a dual carbapenem combination containing imipenem plus meropenem against carbapenem-resistant Acinetobacter baumannii producing carbapenemases OXA-23 or OXA-58. METHODS: An experimental model of peritonitis using C57BL/6J female mice was developed and...

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Detalles Bibliográficos
Autores principales: Cebrero-Cangueiro, T, Nordmann, P, Carretero-Ledesma, M, Pachón, J, Pachón-Ibáñez, M E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879149/
https://www.ncbi.nlm.nih.gov/pubmed/33227138
http://dx.doi.org/10.1093/jac/dkaa487