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Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function

INTRODUCTION: One-third of kidney transplantation patients experience acute kidney injury (AKI) resulting in delayed graft function (DGF), associated with increased risk of graft failure and mortality. Preclinical and phase 2 data indicate that treatment with ANG-3777 (formerly BB3), a hepatocyte gr...

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Detalles Bibliográficos
Autores principales: Vincenti, Flavio, Kim, Jim, Gouveia, Deborah, Pelle, Gabrielle, Mayne, Tracy J., Neylan, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879201/
https://www.ncbi.nlm.nih.gov/pubmed/33615054
http://dx.doi.org/10.1016/j.ekir.2020.11.001