Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells

Chemotherapeutic patients with leukemia often relapse and produce drug resistance due to the existence of leukemia stem cells (LSCs). Fibroblast growth factor receptor 3 (FGFR3) signaling mediates the drug resistance of LSCs in chronic myeloid leukemia (CML). However, the function of FGFR3 in acute...

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Detalles Bibliográficos
Autores principales: Guo, Chen, Ran, Qiuju, Sun, Chun, Zhou, Tingting, Yang, Xi, Zhang, Jizhou, Pang, Shifeng, Xiao, Yechen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879375/
https://www.ncbi.nlm.nih.gov/pubmed/33584313
http://dx.doi.org/10.3389/fphar.2020.632809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879375/
https://www.ncbi.nlm.nih.gov/pubmed/33584313
http://dx.doi.org/10.3389/fphar.2020.632809

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