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Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer: An Ancillary Study of the NRG/RTOG 9601 Randomized Clinical Trial

IMPORTANCE: Decipher (Decipher Biosciences Inc) is a genomic classifier (GC) developed to estimate the risk of distant metastasis (DM) after radical prostatectomy (RP) in patients with prostate cancer. OBJECTIVE: To validate the GC in the context of a randomized phase 3 trial. DESIGN, SETTING, AND P...

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Detalles Bibliográficos
Autores principales: Feng, Felix Y., Huang, Huei-Chung, Spratt, Daniel E., Zhao, Shuang (George), Sandler, Howard M., Simko, Jeffry P., Davicioni, Elai, Nguyen, Paul L., Pollack, Alan, Efstathiou, Jason A., Dicker, Adam P., Todorovic, Tamara, Margrave, Jennifer, Liu, Yang (Seagle), Dabbas, Bashar, Thompson, Darby J. S., Das, Rajdeep, Dignam, James J., Sweeney, Christopher, Attard, Gerhardt, Bahary, Jean-Paul, Lukka, Himanshu R., Hall, William A., Pisansky, Thomas M., Shah, Amit B., Pugh, Stephanie L., Shipley, William U., Tran, Phuoc T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879385/
https://www.ncbi.nlm.nih.gov/pubmed/33570548
http://dx.doi.org/10.1001/jamaoncol.2020.7671