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Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts in vitro cytostatic effects in human colorectal cancer via activating the ROS/p38 and AKT signaling pathways

Colorectal cancer (CRC) is a life-threatening malignant tumor of the digestive tract. Diverse gene mutations and complicated alterations to the signaling pathways in CRC lead to heterogeneity in response to chemotherapy. Moreover, anticancer drugs for CRC chemotherapy are limited due to adverse even...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Yuan, Xiaohui, Yu, Tingting, Huang, Huakun, Yang, Chunmei, Zhang, Lulu, Yang, Shengdong, Luo, Xiaoji, Luo, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879421/
https://www.ncbi.nlm.nih.gov/pubmed/33649853
http://dx.doi.org/10.3892/or.2021.7970