cMyBP-C phosphorylation modulates the time-dependent slowing of unloaded shortening in murine skinned myocardium

In myocardium, phosphorylation of cardiac myosin-binding protein-C (cMyBP-C) is thought to modulate the cooperative activation of the thin filament by binding to myosin and/or actin, thereby regulating the probability of cross-bridge binding to actin. At low levels of Ca(2+) activation, unloaded sho...

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Detalles Bibliográficos
Autores principales: Giles, Jasmine, Fitzsimons, Daniel P., Patel, Jitandrakumar R., Knudtsen, Chloe, Neuville, Alexander J., Moss, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879488/
https://www.ncbi.nlm.nih.gov/pubmed/33566084
http://dx.doi.org/10.1085/jgp.202012782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879488/
https://www.ncbi.nlm.nih.gov/pubmed/33566084
http://dx.doi.org/10.1085/jgp.202012782

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