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Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin

BACKGROUND: Colorectal familial adenomatous polyposis (FAP) adenomas exhibit a uniform pathogenetic basis caused by a germline mutation in the adenomatous polyposis gene (APC), but the molecular changes leading to their development are incompletely understood. However, dysregulated apoptosis is know...

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Detalles Bibliográficos
Autores principales: Roser, Christoph, Tóth, Csaba, Renner, Marcus, Herpel, Esther, Schirmacher, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879509/
https://www.ncbi.nlm.nih.gov/pubmed/33579312
http://dx.doi.org/10.1186/s12964-020-00702-x