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Insights into the unique characteristics of hepatitis C virus genotype 3 revealed by development of a robust sub-genomic DBN3a replicon

Hepatitis C virus (HCV) is an important human pathogen causing 400 000 chronic liver disease-related deaths annually. Until recently, the majority of laboratory-based investigations into the biology of HCV have focused on the genotype 2 isolate, JFH-1, involving replicons and infectious cell culture...

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Detalles Bibliográficos
Autores principales: Ward, Joseph C., Bowyer, Sebastian, Chen, Shucheng, Fernandes Campos, Guilherme Rodrigues, Ramirez, Santseharay, Bukh, Jens, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879556/
https://www.ncbi.nlm.nih.gov/pubmed/32897181
http://dx.doi.org/10.1099/jgv.0.001486