Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture

BACKGROUND: Germinal matrix intraventricular hemorrhage (GM-IVH) is associated with deposition of redox active cell-free hemoglobin (Hb), derived from hemorrhagic cerebrospinal fluid (CSF), in the cerebrum and cerebellum. In a recent study, using a preterm rabbit pup model of IVH, intraventricularly...

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Detalles Bibliográficos
Autores principales: Agyemang, Alex Adusei, Kvist, Suvi Vallius, Brinkman, Nathan, Gentinetta, Thomas, Illa, Miriam, Ortenlöf, Niklas, Holmqvist, Bo, Ley, David, Gram, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879625/
https://www.ncbi.nlm.nih.gov/pubmed/33573677
http://dx.doi.org/10.1186/s12974-020-02052-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879625/
https://www.ncbi.nlm.nih.gov/pubmed/33573677
http://dx.doi.org/10.1186/s12974-020-02052-4

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