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PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
BACKGROUND: Abnormal neovascularization is the most common cause of blindness, and hypoxia alters tissue metabolism, function, and morphology. HIF-1α, the transcriptional activator of VEGF, has intricate mechanisms of nuclear translocation and activation, but its signal termination mechanisms remain...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879653/ https://www.ncbi.nlm.nih.gov/pubmed/33573690 http://dx.doi.org/10.1186/s12964-020-00684-w |