PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function

BACKGROUND: Abnormal neovascularization is the most common cause of blindness, and hypoxia alters tissue metabolism, function, and morphology. HIF-1α, the transcriptional activator of VEGF, has intricate mechanisms of nuclear translocation and activation, but its signal termination mechanisms remain...

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Detalles Bibliográficos
Autores principales: Dong, Lijie, Li, Wenbo, Lin, Tingting, Liu, Boshi, Hong, Yaru, Zhang, Xiaomin, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879653/
https://www.ncbi.nlm.nih.gov/pubmed/33573690
http://dx.doi.org/10.1186/s12964-020-00684-w

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