Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation

BACKGROUND: Amyloid aggregate deposition is the key feature of Alzheimer’s disease. The proteinaceous aggregates found in the afflicted brain are the intra-neuronal neurofibrillary tangles formed by the microtubule-associated protein Tau and extracellular deposits, senile plaques, of amyloid beta (A...

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Detalles Bibliográficos
Autores principales: Sonawane, Shweta Kishor, Uversky, Vladimir N., Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879681/
https://www.ncbi.nlm.nih.gov/pubmed/33579328
http://dx.doi.org/10.1186/s12964-021-00704-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879681/
https://www.ncbi.nlm.nih.gov/pubmed/33579328
http://dx.doi.org/10.1186/s12964-021-00704-3

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