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Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation
BACKGROUND: Amyloid aggregate deposition is the key feature of Alzheimer’s disease. The proteinaceous aggregates found in the afflicted brain are the intra-neuronal neurofibrillary tangles formed by the microtubule-associated protein Tau and extracellular deposits, senile plaques, of amyloid beta (A...
Autores principales: | Sonawane, Shweta Kishor, Uversky, Vladimir N., Chinnathambi, Subashchandrabose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879681/ https://www.ncbi.nlm.nih.gov/pubmed/33579328 http://dx.doi.org/10.1186/s12964-021-00704-3 |
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