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Polytherapeutic strategies with oncolytic virus–bortezomib and adjuvant NK cells in cancer treatment
Proteasome inhibition and oncolytic virotherapy are two emerging targeted cancer therapies. Bortezomib, a proteasome inhibitor, disrupts the degradation of proteins in the cell leading to accumulation of unfolded proteins inducing apoptosis. On the other hand, oncolytic virotherapy uses genetically...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879760/ https://www.ncbi.nlm.nih.gov/pubmed/33402021 http://dx.doi.org/10.1098/rsif.2020.0669 |