Cargando…

Polytherapeutic strategies with oncolytic virus–bortezomib and adjuvant NK cells in cancer treatment

Proteasome inhibition and oncolytic virotherapy are two emerging targeted cancer therapies. Bortezomib, a proteasome inhibitor, disrupts the degradation of proteins in the cell leading to accumulation of unfolded proteins inducing apoptosis. On the other hand, oncolytic virotherapy uses genetically...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aspirin, Angelica P., de los Reyes V, Aurelio A., Kim, Yangjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2021
Materias:	Life Sciences–Mathematics interface
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879760/ https://www.ncbi.nlm.nih.gov/pubmed/33402021 http://dx.doi.org/10.1098/rsif.2020.0669

Ejemplares similares

Evolution of reproductive strategies in incipient multicellularity
por: Gao, Yuanxiao, et al.
Publicado: (2022)

Uncertainty drives deviations in normative foraging decision strategies
por: Kilpatrick, Zachary P., et al.
Publicado: (2021)

Understanding cellular growth strategies via optimal control
por: Mononen, Tommi, et al.
Publicado: (2023)

Evaluating strategies for spatial allocation of vaccines based on risk and centrality
por: Singer, Benjamin J., et al.
Publicado: (2022)

Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians
por: Drawert, Brian, et al.
Publicado: (2017)

Evolution of coordinated punishment to enforce cooperation from an unbiased strategy space
por: García, Julián, et al.
Publicado: (2019)

Agent-based simulations for protecting nursing homes with prevention and vaccination strategies
por: Lasser, Jana, et al.
Publicado: (2021)

Optimal strategies to protect a sub-population at risk due to an established epidemic
por: Bussell, Elliott H., et al.
Publicado: (2022)

Integrated human-virus metabolic stoichiometric modelling predicts host-based antiviral targets against Chikungunya, Dengue and Zika viruses
por: Aller, Sean, et al.
Publicado: (2018)

Optimal COVID-19 lockdown strategies in an age-structured SEIR model of Northern Ireland
por: Abernethy, Gavin M., et al.
Publicado: (2022)

Vaccination strategies when vaccines are scarce: on conflicts between reducing the burden and avoiding the evolution of escape mutants
por: Geoffroy, Félix, et al.
Publicado: (2022)

A novel approach for predicting risk of vector-borne disease establishment in marginal temperate environments under climate change: West Nile virus in the UK
por: Ewing, David A., et al.
Publicado: (2021)

Integrated vaccination and non-pharmaceutical interventions based strategies in Ontario, Canada, as a case study: a mathematical modelling study
por: Betti, Matthew, et al.
Publicado: (2021)

Understanding the within-host dynamics of influenza A virus: from theory to clinical implications
por: Hadjichrysanthou, Christoforos, et al.
Publicado: (2016)

Transmission models indicate Ebola virus persistence in non-human primate populations is unlikely
por: Hayman, David T. S., et al.
Publicado: (2022)

Platforms for Personalized Polytherapeutics Discovery in COVID-19
por: Hopkins, Christopher, et al.
Publicado: (2021)

Infection dynamics in ecosystems: on the interaction between red and grey squirrels, pox virus, pine martens and trees
por: Roberts, M. G., et al.
Publicado: (2021)

Hepatitis C virus modelled as an indirectly transmitted infection highlights the centrality of injection drug equipment in disease dynamics
por: Miller-Dickson, Miles D., et al.
Publicado: (2019)

Optimizing the early detection of low pathogenic avian influenza H7N9 virus in live bird markets
por: Guinat, Claire, et al.
Publicado: (2021)

Sub-spreading events limit the reliable elimination of heterogeneous epidemics
por: Parag, Kris V.
Publicado: (2021)

The ensemble of gene regulatory networks at mutation–selection balance
por: Yang, Chia-Hung, et al.
Publicado: (2023)

The mechanics and interactions of electrically sensitive mechanoreceptive hair arrays of arthropods
por: Palmer, Ryan A., et al.
Publicado: (2022)

Deciphering early-warning signals of SARS-CoV-2 elimination and resurgence from limited data at multiple scales
por: Parag, Kris V., et al.
Publicado: (2021)

Model-based image analysis of a tethered Brownian fibre for shear stress sensing
por: Gallagher, M. T., et al.
Publicado: (2017)

Beyond R(0): heterogeneity in secondary infections and probabilistic epidemic forecasting
por: Hébert-Dufresne, Laurent, et al.
Publicado: (2020)

Understanding the ontogeny of foraging behaviour: insights from combining marine predator bio-logging with satellite-derived oceanography in hidden Markov models
por: Grecian, W. James, et al.
Publicado: (2018)

An analysis of time-varying dynamics in electrically sensitive arthropod hairs to understand real-world electrical sensing
por: Palmer, Ryan A., et al.
Publicado: (2023)

Infection, inflammation and intervention: mechanistic modelling of epithelial cells in COVID-19
por: Fadai, Nabil T., et al.
Publicado: (2021)

Exploring the high-resolution mapping of gender-disaggregated development indicators
por: Bosco, C., et al.
Publicado: (2017)

School closures reduced social mixing of children during COVID-19 with implications for transmission risk and school reopening policies
por: Head, Jennifer R., et al.
Publicado: (2021)

Optimal regulation of tumour-associated neutrophils in cancer progression
por: de los Reyes, Aurelio A., et al.
Publicado: (2022)

Dynamic similarity promotes interpersonal coordination in joint action
por: Słowiński, Piotr, et al.
Publicado: (2016)

Market analyses of livestock trade networks to inform the prevention of joint economic and epidemiological risks
por: Moslonka-Lefebvre, Mathieu, et al.
Publicado: (2016)

Urban scaling in Europe
por: Bettencourt, Luís M. A., et al.
Publicado: (2016)

Quantitative analysis of harmonic convergence in mosquito auditory interactions
por: Aldersley, Andrew, et al.
Publicado: (2016)

Introduction of rubella-containing-vaccine to Madagascar: implications for roll-out and local elimination
por: Wesolowski, Amy, et al.
Publicado: (2016)

Coalescent models for developmental biology and the spatio-temporal dynamics of growing tissues
por: Smadbeck, Patrick, et al.
Publicado: (2016)

A combined within-host and between-hosts modelling framework for the evolution of resistance to antimalarial drugs
por: Legros, Mathieu, et al.
Publicado: (2016)

Can a linguistic serial founder effect originating in Africa explain the worldwide phonemic cline?
por: Fort, Joaquim, et al.
Publicado: (2016)

Analytical approximations for spatial stochastic gene expression in single cells and tissues
por: Smith, Stephen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0tmvcd9i9iatbp9hrtb6hm3brf