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Estrogen Receptor β1 Expression Patterns Have Different Effects on Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors’ Treatment Response in Epidermal Growth Factor Receptor Mutant Lung Adenocarcinoma

Estrogen receptor β (ERβ) can regulate cellular signaling through non-genomic mechanisms, potentially promoting resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). However, the mechanisms underlying the ERβ-mediated resistance to EGFR TKIs remain poorly understoo...

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Detalles Bibliográficos
Autores principales: Zhang, Lijuan, Tian, Meng, Lin, Jiamao, Zhang, Jianbo, Wang, Haiyong, Li, Zhenxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879979/
https://www.ncbi.nlm.nih.gov/pubmed/33585221
http://dx.doi.org/10.3389/fonc.2020.603883