Neuropathological Characterization of a Dravet Syndrome Knock-In Mouse Model Useful for Investigating Cannabinoid Treatments

Dravet syndrome (DS) is an epileptic syndrome caused by mutations in the Scn1a gene encoding the α1 subunit of the sodium channel Nav1.1, which is associated with febrile seizures that progress to severe tonic-clonic seizures and associated comorbidities. Treatment with cannabidiol has been approved...

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Detalles Bibliográficos
Autores principales: Satta, Valentina, Alonso, Cristina, Díez, Paula, Martín-Suárez, Soraya, Rubio, Marta, Encinas, Juan M., Fernández-Ruiz, Javier, Sagredo, Onintza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879984/
https://www.ncbi.nlm.nih.gov/pubmed/33584198
http://dx.doi.org/10.3389/fnmol.2020.602801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879984/
https://www.ncbi.nlm.nih.gov/pubmed/33584198
http://dx.doi.org/10.3389/fnmol.2020.602801

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