Cargando…

Neuropathological Characterization of a Dravet Syndrome Knock-In Mouse Model Useful for Investigating Cannabinoid Treatments

Dravet syndrome (DS) is an epileptic syndrome caused by mutations in the Scn1a gene encoding the α1 subunit of the sodium channel Nav1.1, which is associated with febrile seizures that progress to severe tonic-clonic seizures and associated comorbidities. Treatment with cannabidiol has been approved...

Descripción completa

Detalles Bibliográficos
Autores principales:	Satta, Valentina, Alonso, Cristina, Díez, Paula, Martín-Suárez, Soraya, Rubio, Marta, Encinas, Juan M., Fernández-Ruiz, Javier, Sagredo, Onintza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879984/ https://www.ncbi.nlm.nih.gov/pubmed/33584198 http://dx.doi.org/10.3389/fnmol.2020.602801

Ejemplares similares

Retinal Tissue Shows Glial Changes in a Dravet Syndrome Knock-in Mouse Model
por: Salazar, Juan J., et al.
Publicado: (2023)

Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome
por: Rubio, Marta, et al.
Publicado: (2016)

Editorial: Cannabinoids as potential treatment for neurological diseases
por: Gómez-Cañas, María, et al.
Publicado: (2022)

Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome
por: Martín-Suárez, Soraya, et al.
Publicado: (2020)

Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology
por: Catarino, Claudia B., et al.
Publicado: (2011)

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model
por: Griffin, Aliesha, et al.
Publicado: (2020)

Generation and Characterization of the Drosophila melanogaster paralytic Gene Knock-Out as a Model for Dravet Syndrome
por: Tapia, Andrea, et al.
Publicado: (2021)

Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
por: Benskey, Matthew J., et al.
Publicado: (2023)

Effects of a Sativex-Like Combination of Phytocannabinoids on Disease Progression in R6/2 Mice, an Experimental Model of Huntington’s Disease
por: Valdeolivas, Sara, et al.
Publicado: (2017)

Dravet syndrome
por: Incorpora, Gemma
Publicado: (2009)

Vaccinations and Dravet Syndrome
por: Korff, Christian M.
Publicado: (2015)

Phenotypes of Dravet Syndrome
por: Garcia-Sosa, Rebecca, et al.
Publicado: (2016)

Dravet Syndrome: An Overview
por: Anwar, Arsalan, et al.
Publicado: (2019)

Stiripentol for Dravet syndrome
Publicado: (2020)

Emerging Promise of Cannabinoids for the Management of Pain and Associated Neuropathological Alterations in Alzheimer’s Disease
por: Uddin, Md. Sahab, et al.
Publicado: (2020)

Disordered breathing in a mouse model of Dravet syndrome
por: Kuo, Fu-Shan, et al.
Publicado: (2019)

Neuronal Cell Cycle Re-Entry Enhances Neuropathological Features in App(NLF) Knock-In Mice
por: Barrett, Tomás, et al.
Publicado: (2021)

Auditory or Audiovisual Stimulation Ameliorates Cognitive Impairment and Neuropathology in ApoE4 Knock-In Mice
por: Jung, Harry, et al.
Publicado: (2023)

Crouch Gait in Dravet Syndrome
por: Black, Laura, et al.
Publicado: (2016)

Anesthetic considerations in Dravet syndrome
por: Macdonald‐Laurs, Emma, et al.
Publicado: (2022)

Open the Window for the Cure of Dravet
por: Gu, Bin
Publicado: (2022)

Olivetolic acid, a cannabinoid precursor in Cannabis sativa, but not CBGA methyl ester exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome
por: Anderson, Lyndsey L., et al.
Publicado: (2022)

Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington’s Disease
por: Peng, Qi, et al.
Publicado: (2016)

Do All Roads Lead to Rome? Genes Causing Dravet Syndrome and Dravet Syndrome-Like Phenotypes
por: Ding, Jiangwei, et al.
Publicado: (2022)

Corticohippocampal circuit dysfunction in a mouse model of Dravet syndrome
por: Mattis, Joanna, et al.
Publicado: (2022)

A registry for Dravet syndrome: The Italian experience
por: Balestrini, Simona, et al.
Publicado: (2023)

Fatal Status Epilepticus in Dravet Syndrome
por: De Liso, Paola, et al.
Publicado: (2020)

Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome
por: Gerbatin, Rogério R., et al.
Publicado: (2022)

Long-term Efficacy of Perampanel in a Child with Dravet Syndrome
por: Turón-Viñas, Eulàlia, et al.
Publicado: (2021)

Tau Reduction Prevents Disease in a Mouse Model of Dravet Syndrome
por: Gheyara, Ania L, et al.
Publicado: (2014)

Perampanel Reduces Hyperthermia-Induced Seizures in Dravet Syndrome Mouse Model
por: Ho, Shih-Yin, et al.
Publicado: (2021)

Ictal vocalizations in the Scn1a (+/−) mouse model of Dravet syndrome
por: Anderson, Lyndsey L., et al.
Publicado: (2023)

Knock-In Mouse Models to Investigate the Functions of Opioid Receptors in vivo
por: Degrandmaison, Jade, et al.
Publicado: (2022)

Incidence of Dravet Syndrome in a US Population
por: Krueger, Jena, et al.
Publicado: (2015)

Audit of use of stiripentol in adults with Dravet syndrome
por: Balestrini, S., et al.
Publicado: (2016)

Dravet Syndrome: A Developmental and Epileptic Encephalopathy
por: Lopez-Santiago, Luis, et al.
Publicado: (2019)

Fenfluramine: New Treatment for Seizures in Dravet Syndrome
por: Pierce, Joanna Garcia, et al.
Publicado: (2020)

Dravet Syndrome—The Polish Family’s Perspective Study
por: Paprocka, Justyna, et al.
Publicado: (2021)

Patient with Dravet syndrome: A case report
por: Yadav, Rukesh, et al.
Publicado: (2022)

International consensus on diagnosis and management of Dravet syndrome
por: Wirrell, Elaine C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_he4uisjv052nb5db9rufo73fd6