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Searching for a Putative Mechanism of RIZ2 Tumor-Promoting Function in Cancer Models

Positive Regulatory Domain (PRDM) gene family members commonly express two main molecular variants, the PR-plus isoform usually acting as tumor suppressor and the PR-minus one functioning as oncogene. Accordingly, PRDM2/RIZ encodes for RIZ1 (PR-plus) and RIZ2 (PR-minus). In human cancers, genetic or...

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Detalles Bibliográficos
Autores principales: Rienzo, Monica, Sorrentino, Anna, Di Zazzo, Erika, Di Donato, Marzia, Carafa, Vincenzo, Marino, Maria Michela, De Rosa, Caterina, Gazzerro, Patrizia, Castoria, Gabriella, Altucci, Lucia, Casamassimi, Amelia, Abbondanza, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880127/
https://www.ncbi.nlm.nih.gov/pubmed/33585202
http://dx.doi.org/10.3389/fonc.2020.583533