Molecular mechanism of mureidomycin biosynthesis activated by introduction of an exogenous regulatory gene ssaA into Streptomyces roseosporus

Mureidomycins (MRDs), a group of unique uridyl-peptide antibiotics, exhibit antibacterial activity against the highly refractory pathogen Pseudomonas aeruginosa. Our previous study showed that the cryptic MRD biosynthetic gene cluster (BGC) mrd in Streptomyces roseosporus NRRL 15998 could not be act...

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Detalles Bibliográficos
Autores principales: Liu, Ning, Guan, Hanye, Niu, Guoqing, Jiang, Lingjuan, Li, Yue, Zhang, Jihui, Li, Jine, Tan, Huarong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880210/
https://www.ncbi.nlm.nih.gov/pubmed/33580428
http://dx.doi.org/10.1007/s11427-020-1892-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880210/
https://www.ncbi.nlm.nih.gov/pubmed/33580428
http://dx.doi.org/10.1007/s11427-020-1892-3

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