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ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum

During the process of aging, the retina exhibits chronic oxidative stress (OS) damage. Our preliminary experiment showed that acetaldehyde dehydrogenase 2 (ALDH2) could alleviate retinal damage caused by OS. This study aimed to explore whether ALDH2 could inhibit mice retinal cell apoptosis and enha...

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Detalles Bibliográficos
Autores principales: Long, Pan, He, Mengshan, Yan, Weiming, Chen, Wei, Wei, Dongyu, Wang, Siwang, Zhang, Zuoming, Ge, Wei, Chen, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880320/
https://www.ncbi.nlm.nih.gov/pubmed/33411685
http://dx.doi.org/10.18632/aging.202325