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The mutational pattern of homologous recombination-related (HRR) genes in Chinese colon cancer and its relevance to immunotherapy responses

Background: Microsatellite-stable (MSS) colon adenocarcinoma (COAD) patients are not sensitive to immune checkpoint inhibitors. Here, we focused on analyzing the relationship between homologous recombination repair (HRR)-related gene mutations and clinical immunotherapy responses in MSS COAD. Method...

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Detalles Bibliográficos
Autores principales: Zhou, Pei, Wu, Xueying, Chen, Huan, Hu, Ying, Zhang, Henghui, Wu, Lijia, Yang, Ying, Mao, Beibei, Wang, Huaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880324/
https://www.ncbi.nlm.nih.gov/pubmed/33318301
http://dx.doi.org/10.18632/aging.202267