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MiR-16-5p suppresses myofibroblast activation in systemic sclerosis by inhibiting NOTCH signaling

Systemic sclerosis (SSc) is a prototypic fibrotic disease characterized by localized or diffuse skin thickening and fibrosis. Tissue fibrosis is driven by myofibroblasts, and factors affecting myofibroblast activation may also be involved in the development of SSc. In this study, we examined molecul...

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Detalles Bibliográficos
Autores principales: Yao, Qicen, Xing, Yixi, Wang, Zaiyan, Liang, Jin, Lin, Qianqi, Huang, Meiqiong, Chen, Yiling, Lin, Bo, Xu, Xiayu, Chen, Weifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880343/
https://www.ncbi.nlm.nih.gov/pubmed/33411678
http://dx.doi.org/10.18632/aging.202308