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The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice

Histone modifications, specifically in the lysine residues of histone H3, have been implicated in lifespan regulation in several model organisms. Our previous studies showed that growth hormone (GH) treatment during early life can dramatically influence lifespan in long-lived Ames dwarf mice. Howeve...

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Detalles Bibliográficos
Autores principales: Zhang, Fang, Icyuz, Mert, Bartke, Andrzej, Sun, Liou Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880366/
https://www.ncbi.nlm.nih.gov/pubmed/33378746
http://dx.doi.org/10.18632/aging.202451