FX5 as a non-steroidal GR antagonist improved glucose homeostasis in type 2 diabetic mice via GR/HNF4α/miR-122-5p pathway

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by glucose metabolic disorders, and gluconeogenesis inhibiting is a promisingly therapeutic strategy for T2DM. Glucocorticoid receptor (GR) is tightly implicated in the regulation of gluconeogenesis, although the underlying...

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Detalles Bibliográficos
Autores principales: Xu, Xin, Chen, Yidi, Zhu, Danyang, Zhao, Tong, Xu, Rui, Wang, Jiaying, Hu, Lihong, Shen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880398/
https://www.ncbi.nlm.nih.gov/pubmed/33316780
http://dx.doi.org/10.18632/aging.202275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880398/
https://www.ncbi.nlm.nih.gov/pubmed/33316780
http://dx.doi.org/10.18632/aging.202275

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