PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury

Patients with acute liver failure (ALF) have systemic innate immune suppression and increased susceptibility to infections. Programmed cell death 1 (PD-1) expression by macrophages has been associated with immune suppression during sepsis and cancer. We therefore examined the role of the programmed...

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Detalles Bibliográficos
Autores principales: Triantafyllou, Evangelos, Gudd, Cathrin L.C., Mawhin, Marie-Anne, Husbyn, Hannah C., Trovato, Francesca M., Siggins, Matthew K., O’Connor, Thomas, Kudo, Hiromi, Mukherjee, Sujit K., Wendon, Julia A., Bernsmeier, Christine, Goldin, Robert D., Botto, Marina, Khamri, Wafa, McPhail, Mark J.W., Possamai, Lucia A., Woollard, Kevin J., Antoniades, Charalambos G., Thursz, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880414/
https://www.ncbi.nlm.nih.gov/pubmed/33320839
http://dx.doi.org/10.1172/JCI140196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880414/
https://www.ncbi.nlm.nih.gov/pubmed/33320839
http://dx.doi.org/10.1172/JCI140196

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