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The PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation

Influenza A virus (IAV) has evolved various strategies to counteract the innate immune response using different viral proteins. However, the mechanism is not fully elucidated. In this study, we identified the PB1 protein of H7N9 virus as a new negative regulator of virus- or poly(I:C)-stimulated IFN...

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Detalles Bibliográficos
Autores principales: Zeng, Yan, Xu, Shuai, Wei, Yanli, Zhang, Xuegang, Wang, Qian, Jia, Yane, Wang, Wanbing, Han, Lu, Chen, Zhaoshan, Wang, Zhengxiang, Zhang, Bo, Chen, Hualan, Lei, Cao-Qi, Zhu, Qiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880438/
https://www.ncbi.nlm.nih.gov/pubmed/33577621
http://dx.doi.org/10.1371/journal.ppat.1009300