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Brownian dynamics simulation of protofilament relaxation during rapid freezing

Electron cryo-microscopy (Cryo-EM) is a powerful method for visualizing biological objects with up to near-angstrom resolution. Instead of chemical fixation, the method relies on very rapid freezing to immobilize the sample. Under these conditions, crystalline ice does not have time to form and dist...

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Detalles Bibliográficos
Autores principales: Ulyanov, Evgeniy V., Vinogradov, Dmitrii S., McIntosh, J. Richard, Gudimchuk, Nikita B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880439/
https://www.ncbi.nlm.nih.gov/pubmed/33577570
http://dx.doi.org/10.1371/journal.pone.0247022