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Echis carinatus snake venom metalloprotease-induced toxicities in mice: Therapeutic intervention by a repurposed drug, Tetraethyl thiuram disulfide (Disulfiram)

Echis carinatus (EC) is known as saw-scaled viper and it is endemic to the Indian subcontinent. Envenoming by EC represents a major cause of snakebite mortality and morbidity in the Indian subcontinent. Zinc (Zn(++)) dependent snake venom metalloproteases (SVMPs) present in Echis carinatus venom (EC...

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Detalles Bibliográficos
Autores principales: Rudresha, Gotravalli V., Urs, Amog P., Manjuprasanna, Vaddarahally N., Milan Gowda, Mallanayakanakatte D., Jayachandra, Krishnegowda, Rajaiah, Rajesh, Vishwanath, Bannikuppe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880489/
https://www.ncbi.nlm.nih.gov/pubmed/33529194
http://dx.doi.org/10.1371/journal.pntd.0008596