Submonomeric Strategy with Minimal Protection for the Synthesis of C(2)-Modified Peptide Nucleic Acids

[Image: see text] A novel synthesis of C(2)-modified peptide nucleic acids (PNAs) is proposed, using a submonomeric strategy with minimally protected building blocks, which allowed a reduction in the required synthetic steps. N(3)-unprotected, d-Lys- and d-Arg-based backbones were used to obtain pos...

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Detalles Bibliográficos
Autores principales: Volpi, Stefano, Rozzi, Andrea, Rivi, Nicola, Neri, Martina, Knoll, Wolfgang, Corradini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880566/
https://www.ncbi.nlm.nih.gov/pubmed/33417460
http://dx.doi.org/10.1021/acs.orglett.0c04116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880566/
https://www.ncbi.nlm.nih.gov/pubmed/33417460
http://dx.doi.org/10.1021/acs.orglett.0c04116

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