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Visible-Light-Mediated Oxidative Debenzylation Enables the Use of Benzyl Ethers as Temporary Protecting Groups

[Image: see text] The cleavage of benzyl ethers by catalytic hydrogenolysis or Birch reduction suffers from poor functional group compatibility and limits their use as a protecting group. The visible-light-mediated debenzylation disclosed here renders benzyl ethers temporary protective groups, enabl...

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Detalles Bibliográficos
Autores principales: Cavedon, Cristian, Sletten, Eric T., Madani, Amiera, Niemeyer, Olaf, Seeberger, Peter H., Pieber, Bartholomäus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880570/
https://www.ncbi.nlm.nih.gov/pubmed/33400534
http://dx.doi.org/10.1021/acs.orglett.0c04026