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Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization

The role of protein stabilization in cortical development remains poorly understood. A recessive mutation in the USP11 gene is found in a rare neurodevelopmental disorder with intellectual disability, but its pathogenicity and molecular mechanism are unknown. Here, we show that mouse Usp11 is expres...

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Detalles Bibliográficos
Autores principales: Chiang, Shang-Yin, Wu, Hsin-Chieh, Lin, Shu-Yu, Chen, Hsin-Yi, Wang, Chia-Fang, Yeh, Nai-Hsing, Shih, Jou-Ho, Huang, Yi-Shuian, Kuo, Hung-Chih, Chou, Shen-Ju, Chen, Ruey-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880594/
https://www.ncbi.nlm.nih.gov/pubmed/33579706
http://dx.doi.org/10.1126/sciadv.abc6093