Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle

Circadian rhythms are an integral part of physiology, underscoring their relevance for the treatment of disease. We conducted cell-based high-throughput screening to investigate time-of-day influences on the activity of known antitumor agents and found that many compounds exhibit daily rhythms of cy...

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Detalles Bibliográficos
Autores principales: Lee, Yool, Fong, Shi Yi, Shon, Joy, Zhang, Shirley L., Brooks, Rebekah, Lahens, Nicholas F., Chen, Dechun, Dang, Chi Van, Field, Jeffrey M., Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880601/
https://www.ncbi.nlm.nih.gov/pubmed/33579708
http://dx.doi.org/10.1126/sciadv.abd2645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880601/
https://www.ncbi.nlm.nih.gov/pubmed/33579708
http://dx.doi.org/10.1126/sciadv.abd2645

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