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Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle
Circadian rhythms are an integral part of physiology, underscoring their relevance for the treatment of disease. We conducted cell-based high-throughput screening to investigate time-of-day influences on the activity of known antitumor agents and found that many compounds exhibit daily rhythms of cy...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880601/ https://www.ncbi.nlm.nih.gov/pubmed/33579708 http://dx.doi.org/10.1126/sciadv.abd2645 |