Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome

Mitochondrial dysfunction is an established hallmark of aging and neurodegenerative disorders such as Down syndrome (DS) and Alzheimer’s disease (AD). Using a high-resolution density gradient separation of extracellular vesicles (EVs) isolated from murine and human DS and diploid control brains, we...

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Detalles Bibliográficos
Autores principales: D’Acunzo, Pasquale, Pérez-González, Rocío, Kim, Yohan, Hargash, Tal, Miller, Chelsea, Alldred, Melissa J., Erdjument-Bromage, Hediye, Penikalapati, Sai C., Pawlik, Monika, Saito, Mitsuo, Saito, Mariko, Ginsberg, Stephen D., Neubert, Thomas A., Goulbourne, Chris N., Levy, Efrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880603/
https://www.ncbi.nlm.nih.gov/pubmed/33579698
http://dx.doi.org/10.1126/sciadv.abe5085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880603/
https://www.ncbi.nlm.nih.gov/pubmed/33579698
http://dx.doi.org/10.1126/sciadv.abe5085

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