Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons

Extracellular vesicles are highly transmissible and play critical roles in the propagation of tau pathology, although the underlying mechanism remains elusive. Here, for the first time, we comprehensively characterized the physicochemical structure and pathogenic function of human brain-derived extr...

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Detalles Bibliográficos
Autores principales: Ruan, Zhi, Pathak, Dhruba, Venkatesan Kalavai, Srinidhi, Yoshii-Kitahara, Asuka, Muraoka, Satoshi, Bhatt, Nemil, Takamatsu-Yukawa, Kayo, Hu, Jianqiao, Wang, Yuzhi, Hersh, Samuel, Ericsson, Maria, Gorantla, Santhi, Gendelman, Howard E, Kayed, Rakez, Ikezu, Seiko, Luebke, Jennifer I, Ikezu, Tsuneya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880668/
https://www.ncbi.nlm.nih.gov/pubmed/33246331
http://dx.doi.org/10.1093/brain/awaa376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880668/
https://www.ncbi.nlm.nih.gov/pubmed/33246331
http://dx.doi.org/10.1093/brain/awaa376

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