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Fitness variation across subtle environmental perturbations reveals local modularity and global pleiotropy of adaptation
Building a genotype-phenotype-fitness map of adaptation is a central goal in evolutionary biology. It is difficult even when adaptive mutations are known because it is hard to enumerate which phenotypes make these mutations adaptive. We address this problem by first quantifying how the fitness of hu...
Autores principales: | Kinsler, Grant, Geiler-Samerotte, Kerry, Petrov, Dmitri A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880691/ https://www.ncbi.nlm.nih.gov/pubmed/33263280 http://dx.doi.org/10.7554/eLife.61271 |
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