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A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells
Expression of the andrgogen receptor splice variant 7 (AR-V7) is frequently detected in castrate resistant prostate cancer and associated with resistance to AR-targeted therapies. While we have previously noted that homodimerization is required for the transcriptional activity of AR-V7 and that AR-V...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880901/ https://www.ncbi.nlm.nih.gov/pubmed/33323969 http://dx.doi.org/10.1038/s41388-020-01585-5 |