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A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells

Expression of the andrgogen receptor splice variant 7 (AR-V7) is frequently detected in castrate resistant prostate cancer and associated with resistance to AR-targeted therapies. While we have previously noted that homodimerization is required for the transcriptional activity of AR-V7 and that AR-V...

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Detalles Bibliográficos
Autores principales: Roggero, Carlos M., Jin, Lianjin, Cao, Subing, Sonavane, Rajni, Kopplin, Noa G, Ta, Huy, Ekoue, Dede N, Witwer, Michael, Ma, Shihong, Liu, Hong, Ma, Tianfang, Gioeli, Daniel, Raj, Ganesh V., Dong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880901/
https://www.ncbi.nlm.nih.gov/pubmed/33323969
http://dx.doi.org/10.1038/s41388-020-01585-5