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Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants

Young breast cancer (BC) patients carrying a germline BRCA pathogenic variant (mBRCA) have similar outcomes as non-carriers. However, the impact of the type of gene (BRCA1 vs. BRCA2) and hormone receptor status (positive [HR+] vs. negative [HR−]) on clinical behavior and outcomes of mBRCA BC remains...

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Detalles Bibliográficos
Autores principales: Lambertini, Matteo, Ceppi, Marcello, Hamy, Anne-Sophie, Caron, Olivier, Poorvu, Philip D., Carrasco, Estela, Grinshpun, Albert, Punie, Kevin, Rousset-Jablonski, Christine, Ferrari, Alberta, Paluch-Shimon, Shani, Toss, Angela, Senechal, Claire, Puglisi, Fabio, Pogoda, Katarzyna, Pérez-Fidalgo, Jose Alejandro, De Marchis, Laura, Ponzone, Riccardo, Livraghi, Luca, Estevez-Diz, Maria Del Pilar, Villarreal-Garza, Cynthia, Dieci, Maria Vittoria, Clatot, Florian, Duhoux, Francois P., Graffeo, Rossella, Teixeira, Luis, Córdoba, Octavi, Sonnenblick, Amir, Ferreira, Arlindo R., Partridge, Ann H., Di Meglio, Antonio, Saule, Claire, Peccatori, Fedro A., Bruzzone, Marco, t’Kint de Roodenbeke, Marie Daphne, Ameye, Lieveke, Balmaña, Judith, Del Mastro, Lucia, Azim, Hatem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880991/
https://www.ncbi.nlm.nih.gov/pubmed/33579978
http://dx.doi.org/10.1038/s41523-021-00224-w