CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions

Vertebrate genomes are partitioned into contact domains defined by enhanced internal contact frequency and formed by two principal mechanisms: compartmentalization of transcriptionally active and inactive domains, and stalling of chromosomal loop-extruding cohesin by CTCF bound at domain boundaries....

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Detalles Bibliográficos
Autores principales: Kaushal, Anjali, Mohana, Giriram, Dorier, Julien, Özdemir, Isa, Omer, Arina, Cousin, Pascal, Semenova, Anastasiia, Taschner, Michael, Dergai, Oleksandr, Marzetta, Flavia, Iseli, Christian, Eliaz, Yossi, Weisz, David, Shamim, Muhammad Saad, Guex, Nicolas, Lieberman Aiden, Erez, Gambetta, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880997/
https://www.ncbi.nlm.nih.gov/pubmed/33579945
http://dx.doi.org/10.1038/s41467-021-21366-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880997/
https://www.ncbi.nlm.nih.gov/pubmed/33579945
http://dx.doi.org/10.1038/s41467-021-21366-2

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