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The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms

Pediatric therapy-related myeloid neoplasms (tMN) occur in children after exposure to cytotoxic therapy and have a dismal prognosis. The somatic and germline genomic alterations that drive these myeloid neoplasms in children and how they arise have yet to be comprehensively described. We use whole e...

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Detalles Bibliográficos
Autores principales: Schwartz, Jason R., Ma, Jing, Kamens, Jennifer, Westover, Tamara, Walsh, Michael P., Brady, Samuel W., Robert Michael, J., Chen, Xiaolong, Montefiori, Lindsey, Song, Guangchun, Wu, Gang, Wu, Huiyun, Branstetter, Cristyn, Hiltenbrand, Ryan, Walsh, Michael F., Nichols, Kim E., Maciaszek, Jamie L., Liu, Yanling, Kumar, Priyadarshini, Easton, John, Newman, Scott, Rubnitz, Jeffrey E., Mullighan, Charles G., Pounds, Stanley, Zhang, Jinghui, Gruber, Tanja, Ma, Xiaotu, Klco, Jeffery M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880998/
https://www.ncbi.nlm.nih.gov/pubmed/33579957
http://dx.doi.org/10.1038/s41467-021-21255-8