Cargando…
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms
Pediatric therapy-related myeloid neoplasms (tMN) occur in children after exposure to cytotoxic therapy and have a dismal prognosis. The somatic and germline genomic alterations that drive these myeloid neoplasms in children and how they arise have yet to be comprehensively described. We use whole e...
Autores principales: | Schwartz, Jason R., Ma, Jing, Kamens, Jennifer, Westover, Tamara, Walsh, Michael P., Brady, Samuel W., Robert Michael, J., Chen, Xiaolong, Montefiori, Lindsey, Song, Guangchun, Wu, Gang, Wu, Huiyun, Branstetter, Cristyn, Hiltenbrand, Ryan, Walsh, Michael F., Nichols, Kim E., Maciaszek, Jamie L., Liu, Yanling, Kumar, Priyadarshini, Easton, John, Newman, Scott, Rubnitz, Jeffrey E., Mullighan, Charles G., Pounds, Stanley, Zhang, Jinghui, Gruber, Tanja, Ma, Xiaotu, Klco, Jeffery M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880998/ https://www.ncbi.nlm.nih.gov/pubmed/33579957 http://dx.doi.org/10.1038/s41467-021-21255-8 |
Ejemplares similares
-
Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis
por: Umeda, Masayuki, et al.
Publicado: (2023) -
Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
por: Umeda, Masayuki, et al.
Publicado: (2022) -
The genomic landscape of pediatric myelodysplastic syndromes
por: Schwartz, Jason R., et al.
Publicado: (2017) -
Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells
por: Thomas, Melvin E., et al.
Publicado: (2021) -
Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice
por: Abdelhamed, Sherif, et al.
Publicado: (2022)