Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma

Multiple myeloma (MM) is an aggressive plasma cell neoplasm characterized by genomic heterogeneity. Superenhancers (SEs) are defined as large clusters of enhancers in close genomic proximity, which regulate genes for maintaining cellular identity and promote oncogenic transcription to which cancer c...

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Detalles Bibliográficos
Autores principales: Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Wong, Regina Wan Ju, Chooi, Jing-Yuan, Lim, Julia Sze Lynn, Sanda, Takaomi, Ooi, Melissa, De Mel, Sanjay, Soekojo, Cinnie, Chen, Yongxia, Zhang, Enfan, Cai, Zhen, Shen, Peng, Ruan, Jian, Chng, Wee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881003/
https://www.ncbi.nlm.nih.gov/pubmed/33579893
http://dx.doi.org/10.1038/s41408-021-00421-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881003/
https://www.ncbi.nlm.nih.gov/pubmed/33579893
http://dx.doi.org/10.1038/s41408-021-00421-7

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