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Association of the plasma xanthine oxidoreductase activity with the metabolic parameters and vascular complications in patients with type 2 diabetes

Xanthine oxidoreductase (XOR) catalyzes the oxidation of hypoxanthine to xanthine, and of xanthine to uric acid. XOR also enhances the production of reactive oxygen species and causes endothelial dysfunction. In this study, we evaluated the association of XOR and its substrate with the vascular comp...

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Detalles Bibliográficos
Autores principales: Okuyama, Tomoko, Shirakawa, Jun, Nakamura, Takashi, Murase, Takayo, Miyashita, Daisuke, Inoue, Ryota, Kyohara, Mayu, Togashi, Yu, Terauchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881005/
https://www.ncbi.nlm.nih.gov/pubmed/33580173
http://dx.doi.org/10.1038/s41598-021-83234-9