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Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection

In light of the recent accumulated knowledge on SARS-CoV-2 and its mode of human cells invasion, the binding of viral spike glycoprotein to human Angiotensin Converting Enzyme 2 (hACE2) receptor plays a central role in cell entry. We designed a series of peptides mimicking the N-terminal helix of hA...

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Detalles Bibliográficos
Autores principales: Karoyan, Philippe, Vieillard, Vincent, Gómez-Morales, Luis, Odile, Estelle, Guihot, Amélie, Luyt, Charles-Edouard, Denis, Alexis, Grondin, Pascal, Lequin, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881012/
https://www.ncbi.nlm.nih.gov/pubmed/33580154
http://dx.doi.org/10.1038/s42003-021-01736-8