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Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection
In light of the recent accumulated knowledge on SARS-CoV-2 and its mode of human cells invasion, the binding of viral spike glycoprotein to human Angiotensin Converting Enzyme 2 (hACE2) receptor plays a central role in cell entry. We designed a series of peptides mimicking the N-terminal helix of hA...
Autores principales: | Karoyan, Philippe, Vieillard, Vincent, Gómez-Morales, Luis, Odile, Estelle, Guihot, Amélie, Luyt, Charles-Edouard, Denis, Alexis, Grondin, Pascal, Lequin, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881012/ https://www.ncbi.nlm.nih.gov/pubmed/33580154 http://dx.doi.org/10.1038/s42003-021-01736-8 |
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