AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils

Systemic AA amyloidosis is a world-wide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from serum amyloid A (SAA) protein. Using cryo electron microscopy we here show that amyloid fibrils which were purified from AA amyloidotic mice are st...

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Detalles Bibliográficos
Autores principales: Bansal, Akanksha, Schmidt, Matthias, Rennegarbe, Matthies, Haupt, Christian, Liberta, Falk, Stecher, Sabrina, Puscalau-Girtu, Ioana, Biedermann, Alexander, Fändrich, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881110/
https://www.ncbi.nlm.nih.gov/pubmed/33579941
http://dx.doi.org/10.1038/s41467-021-21129-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881110/
https://www.ncbi.nlm.nih.gov/pubmed/33579941
http://dx.doi.org/10.1038/s41467-021-21129-z

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